Glutamine: Skin rashes

The skin rashes from glutamine are typically due to an allergic reaction to gluten. It is important to note that glutamine is one of the highly abundant amino acids. Glutamine is commonly used by body builders as a supplemental protein.

Wheat is comprised of four main allergic proteins – albumin, gliadin, globulin and gluten. Individuals who have been diagnosed with gluten or wheat allergy should not use glutamine. A doctor should be consulted before taking any supplement.

What are the possible causes?

The exact cause of skin rashes from glutamine is due to an allergic reaction to gluten. During an allergic reaction to glutamine, the immune system of the individual becomes highly sensitive and overly reacts to the protein. The immune system wrongly identifies the protein as a threat to the body and triggers the production of IgE antibodies to fight off glutamine. This starts a chain of chemical reactions in the body that generates the typical symptoms of an allergic reaction.


The common skin rashes from an allergy to glutamine include generalized itchiness, hives and eczema.

Why skin rashes occur?

The common skin rashes from an allergy to glutamine include generalized itchiness, hives and eczema. A general rash can manifest which causes itchiness and inflammation of the skin after the consumption of glutamine.

An allergic reaction to glutamine can instigate eczema among an individual who is predisposed to the skin condition. Take note that eczema appears as blisters, usually on the arms, face and back of the legs. As for hives, they form as clusters with a flattened top and have defined perimeters. Hives are extremely itchy and can take on various sizes and shapes on different parts of the body.

Contact dermatitis involves inflammation of the skin that causes eczema-like blisters that occur after exposure to a particular substance. If an individual is highly sensitive to glutamine, it is recommended to avoid direct exposure or consumption of the product. The symptoms of contact dermatitis can appear within a few minutes after exposure to glutamine.


The skin rashes that occur due to an allergic reaction to glutamine can be managed by identification of the allergen and avoidance of the product. If the individual accidentally consumed glutamine, a doctor should be consulted right away.

The use of topical steroid creams is recommended to calm the skin and reduce the itchiness and inflammation. Hydrocortisone is readily available over-the-counter while corticosteroids might be prescribed in severe cases. In some cases, an oral antihistamine can help reduce the amount of histamine in the body that causes the breakout of skin rashes.

If an individual is allergic to wheat, he/she might run a higher risk of developing a severe allergic reaction upon ingestion of glutamine. A severe allergic reaction can be life-threatening. The typical side effects include an abrupt drop in the blood pressure, dizziness, faint pulse, anxiety and shortness of breath.


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